Multimodal imaging of recovery of functional networks associated with reversal of paradoxical herniation after cranioplasty.

TitleMultimodal imaging of recovery of functional networks associated with reversal of paradoxical herniation after cranioplasty.
Publication TypeJournal Article
Year of Publication2011
AuthorsVoss, Henning U., Heier Linda A., and Schiff Nicholas D.
JournalClin Imaging
Volume35
Issue4
Pagination253-8
Date Published2011 Jul-Aug
ISSN1873-4499
KeywordsBrain Injuries, Decompressive Craniectomy, Female, Fluorodeoxyglucose F18, Humans, Magnetic Resonance Imaging, Positron-Emission Tomography, Radiopharmaceuticals, Reconstructive Surgical Procedures, Recovery of Function, Young Adult
Abstract

Cranioplasty following decompressive craniectomy is reported to result in improved blood flow, cerebral metabolism, and concomitant neurological recovery. We used multimodal functional imaging technology to study a patient with marked neurological recovery after cranioplasty. Resting-state networks and auditory responses obtained with functional MRI and cerebral metabolism obtained with PET before and after cranioplasty revealed significant functional changes that were correlated with the subject's neurological recovery. Our results suggest a link between recovery of behavior, cerebral metabolism, and resting-state networks following cranioplasty.

DOI10.1016/j.clinimag.2010.07.008
Alternate JournalClin Imaging
PubMed ID21724116
PubMed Central IDPMC3129541
Grant ListR01 HD051912-03 / HD / NICHD NIH HHS / United States

Weill Cornell Medicine Consortium for the Advanced Study of Brain Injury 520 East 70th Street New York, NY