Modulation of arousal regulation with central thalamic deep brain stimulation.

TitleModulation of arousal regulation with central thalamic deep brain stimulation.
Publication TypeJournal Article
Year of Publication2009
AuthorsShah, Sudhin A., Baker Jonathan L., Ryou Jae-Wook, Purpura Keith P., and Schiff Nicholas D.
JournalConf Proc IEEE Eng Med Biol Soc
Volume2009
Pagination3314-7
Date Published2009
ISSN1557-170X
KeywordsAdult, Animals, Arousal, Attention, Behavior, Behavior, Animal, Brain, Deep Brain Stimulation, Electrophysiology, Humans, Macaca, Male, Memory, Short-Term, Neural Pathways, Neurons
Abstract

To investigate the effects of central thalamic deep brain stimulation (CT/DBS) on behavior and frontal cortical function, we conducted experiments in an awake, behaving macaque monkey performing tasks that required sustained attention and working memory. Results of this preliminary study revealed that CT/DBS can lead to an improvement, a decrement, a mixed or have no effect on behavior.

DOI10.1109/IEMBS.2009.5333751
Alternate JournalConf Proc IEEE Eng Med Biol Soc
PubMed ID19964301

Weill Cornell Medicine Consortium for the Advanced Study of Brain Injury 520 East 70th Street New York, NY