Central Lateral Thalamic Nucleus Stimulation Awakens Cortex via Modulation of Cross-Regional, Laminar-Specific Activity during General Anesthesia.

TitleCentral Lateral Thalamic Nucleus Stimulation Awakens Cortex via Modulation of Cross-Regional, Laminar-Specific Activity during General Anesthesia.
Publication TypeJournal Article
Year of Publication2020
AuthorsSchiff, Nicholas D.
JournalNeuron
Volume106
Issue1
Pagination1-3
Date Published2020 04 08
ISSN1097-4199
KeywordsAnesthesia, General, Consciousness, Electric Stimulation, Intralaminar Thalamic Nuclei, Neurons, Thalamus
Abstract

Experiments identify cortical layer specific effects during induced arousal from general anesthesia. In this issue of Neuron, Redinbaugh et al. (2020) find evidence that central lateral thalamic nucleus electrical stimulation reactivates the cortex by restoring deep-layer firing rates and modulating feedforward and feedback connectivity.

DOI10.1016/j.neuron.2020.02.016
Alternate JournalNeuron
PubMed ID32272061

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