The role of arousal and "gating" systems in the neurology of impaired consciousness.

TitleThe role of arousal and "gating" systems in the neurology of impaired consciousness.
Publication TypeJournal Article
Year of Publication2000
AuthorsSchiff, N D., and Plum F
JournalJ Clin Neurophysiol
Volume17
Issue5
Pagination438-52
Date Published2000 Sep
ISSN0736-0258
KeywordsArousal, Brain, Coma, Consciousness Disorders, Delirium, Dementia, Humans, Mutism, Nerve Net, Neuropsychological Tests, Persistent Vegetative State, Prosencephalon, Seizures, Sensation Disorders
Abstract

A brief taxonomy of neurologic disorders resulting in global impairments of consciousness is presented. Particular emphasis is placed on focal injuries of subcortical structures that may produce disorders that are otherwise associated to large bilateral cortical injuries. A distinction between subcortical arousal and "gating" systems is developed. Both clinical and experimental studies are reviewed in the context of these disorders and their possible underlying mechanisms.

Alternate JournalJ Clin Neurophysiol
PubMed ID11085547

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